Publications



Stromal cell protein kinase C-beta inhibition enhances chemosensitivity in B cell malignancies and overcomes drug resistance


Park, E., Chen, J., Moore, A., Mangolini, M., Santoro, A., Boyd, J. R., Schjerven, H., Ecker, V., Buchner, M., Williamson, J. C., Lehner, P. J., Gasparoli, L., Williams, O., Bloehdorn, J., Stilgenbauer, S., Leitges, M., Egle, A., Schmidt-Supprian, M., Frietze, S., Ringshausen, I. (2020). Sci Transl Med 12.

DOI:10.1126/scitranslmed.aax9340(link is external)

MCL-1 gains occur with high frequency in lung adenocarcinoma and can be targeted therapeutically


Munkhbaatar, E., Dietzen, M., Agrawal, D., Anton, M., Jesinghaus, M., Boxberg, M., Pfarr, N., Bidola, P., Uhrig, S., Hockendorf, U., Meinhardt, A. L., Wahida, A., Heid, I., Braren, R., Mishra, R., Warth, A., Muley, T., Poh, P. S. P., Wang, X., Frohling, S., Steiger, K., Slotta-Huspenina, J., van Griensven, M., Pfeiffer, F., Lange, S., Rad, R., Spella, M., Stathopoulos, G. T., Ruland, J., Bassermann, F., Weichert, W., Strasser, A., Branca, C., Heikenwalder, M., Swanton, C., McGranahan, N., Jost, P. J. (2020). Nat Commun 11, 4527.

DOI:10.1038/s41467-020-18372-1

ER Stress and the UPR in Shaping Intestinal Tissue Homeostasis and Immunity


Coleman, O. I. and Haller, D. (2019). Front Immunol 10, 2825.

DOI:10.3389/fimmu.2019.02825(link is external)

Targeting tumor-resident mast cells for effective anti-melanoma immune responses


Kaesler, S., Wolbing, F., Kempf, W. E., Skabytska, Y., Koberle, M., Volz, T., Sinnberg, T., Amaral, T., Mockel, S., Yazdi, A., Metzler, G., Schaller, M., Hartmann, K., Weide, B., Garbe, C., Rammensee, H. G., Rocken, M., Biedermann, T. (2019). JCI Insight 4.

DOI:10.1172/jci.insight.125057(link is external)

The uric acid crystal receptor Clec12A potentiates type I interferon responses


Li, K., Neumann, K., Duhan, V., Namineni, S., Hansen, A. L., Wartewig, T., Kurgyis, Z., Holm, C. K., Heikenwalder, M., Lang, K. S., Ruland, J. (2019). Proc Natl Acad Sci USA 116, 18544-18549.

DOI:10.1073/pnas.1821351116(link is external)

Biodegradable Fluorescent Nanoparticles for Endoscopic Detection of Colorectal Carcinogenesis


Rogalla, S., Flisikowski, K., Gorpas, D., Mayer, A. T., Flisikowska, T., Mandella, M. J., Ma, X. P., Casey, K. M., Felt, S. A., Saur, D., Ntziachristos, V., Schnieke, A., Contag, C. H., Gambhir, S. S., Harmsen, S. (2019). Adv Funct Mater 29.

DOI:10.1002/adfm.201904992(link is external)

Gene editing enables T-cell engineering to redirect antigen specificity for potent tumor rejection


Albers, J.J., Ammon, T., Gosmann, D., Audehm, S., Thoene, S., Winter, C., Secci, R., Wolf, A., Stelzl, A., Steiger, K., Ruland, J., Bassermann, F., Kupatt, C., Anton, M., Krackhardt, A.M. (2019). Life Sci Alliance 2.

DOI: 10.26508/lsa.201900367(link is external)

CARD-BCL-10-MALT1 signalling in protective and pathological immunity


Ruland, J. and Hartjes, L. (2019). Nat Rev Immunol 19, 118-134.

DOI: 10.1038/s41577-018-0087-2(link is external)

Understanding the Functional Properties of Neonatal Dendritic Cells: A Doorway to Enhance Vaccine Effectiveness?


Papaioannou, N.E., Pasztoi, M., and Schraml, B.U. (2019). Front Immunol 9, 3123.

DOI: 10.3389/fimmu.2018.03123(link is external)

Radiation-Induced Amplification of TGFB1-Induced Mesenchymal Stem Cell-Mediated Sodium Iodide Symporter (NIS) Gene I-131 Therapy


Schug, C., Kitzberger, C., Sievert, W., Spellerberg, R., Tutter, M., Schmohl, K. A., Eberlein, B., Biedermann, T., Steiger, K., Zach, C., Schwaiger, M., Multhoff, G., Wagner, E., Nelson, P. J., Spitzweg, C. (2019). Clin Cancer Res 25, 5997-6008.

DOI:10.1158/1078-0432.Ccr-18-4092(link is external)