Publications



MALT1 protease function in regulatory T cells induces MYC activity to promote mitochondrial function and cellular expansion


Rosenbaum, M., Schnalzger, T., Engleitner, T., Weiss, C., Mishra, R., Mibus, C., Mitterer, T., Rad, R., Ruland, J. (2021). Eur J Immunol.

DOI:10.1002/eji.202149355

CHIP and hips: clonal hematopoiesis is common in patients undergoing hip arthroplasty and is associated with autoimmune disease


Hecker, J.S., Hartmann, L., Riviere, J., Buck, M.C., van der Garde, M., Rothenberg-Thurley, M., Fischer, L., Winter, S., Ksienzyk, B., Ziemann, F., Solovey, M., Rauner, M., Tsourdi, E., Sockel, K., Schneider, M., Kubasch, A.S., Nolde, M., Hausmann, D., Paulus, A.C., Lutzner, J., Roth, A., Bassermann, F., Spiekermann, K., Marr, C., Hofbauer, L.C., Platzbecker, U., Metzeler, K.H., Gotze, K.S. (2021). Blood 138, 1727-1732.

DOI:10.1182/blood.2020010163

Multiple Myeloma: Molecular Pathogenesis and Disease Evolution


Heider, M., Nickel, K., Hogner, M., Bassermann, F. (2021). Oncol Res Treat 1-8.

DOI:10.1159/000520312

Immunotherapies for hepatocellular carcinoma


Llovet, J.M., Castet, F., Heikenwalder, M., Maini, M.K., Mazzaferro, V., Pinato, D.J., Pikarsky, E., Zhu, A.X., Finn, R.S. (2021). Nat Rev Clin Oncol.

DOI:10.1038/s41571-021-00573-2

TRAF6 prevents fatal inflammation by homeostatic suppression of MALT1 protease


O'Neill, T.J., Seeholzer, T., Gewies, A., Gehring, T., Giesert, F., Hamp, I., Grass, C., Schmidt, H., Kriegsmann, K., Tofaute, M.J., Demski, K., Poth, T., Rosenbaum, M., Schnalzger, T., Ruland, J., Gottlicher, M., Kriegsmann, M., Naumann, R., Heissmeyer, V., Plettenburg, O., Wurst, W., Krappmann, D. (2021). Sci Immunol 6, eabh2095.

DOI:10.1126/sciimmunol.abh2095

Human immune disorder associated with homozygous hypomorphic mutation affecting MALT1B splice variant


Kutukculer, N., Seeholzer, T., O'Neill, T. J., Grass, C., Aykut, A., Karaca, N. E., Durmaz, A., Cogulu, O., Aksu, G., Gehring, T., Gewies, A., Krappmann, D. (2021). J Allergy Clin Immunol 147, 775-778.e8.

DOI:10.1016/j.jaci.2020.07.034(link is external)

Editorial for Molecular Immunology - Special issue "Novel concepts in dendritic cell development


Schraml, B. U., Krug, A. B. (2021). Mol Immunol 129, 112-113.

DOI:10.1016/j.molimm.2020.12.001(link is external)

SUMO pathway inhibition targets an aggressive pancreatic cancer subtype


Biederstadt, A., Hassan, Z., Schneeweis, C., Schick, M., Schneider, L., Muckenhuber, A., Hong, Y., Siegers, G., Nilsson, L., Wirth, M., Dantes, Z., Steiger, K., Schunck, K., Langston, S., Lenhof, H. P., Coluccio, A., Orben, F., Slawska, J., Scherger, A., Saur, D., Muller, S., Rad, R., Weichert, W., Nilsson, J., Reichert, M., Schneider, G., Keller, U. (2020). Gut 69, 1472-1482.

DOI:10.1136/gutjnl-2018-317856

Analysis pipelines for cancer genome sequencing in mice


Lange, S., Engleitner, T., Mueller, S., Maresch, R., Zwiebel, M., Gonzalez-Silva, L., Schneider, G., Banerjee, R., Yang, F. T., Vassiliou, G. S., Friedrich, M. J., Saur, D., Varela, I., Rad, R. (2020). Nat Protoc 15, 266-315.

DOI:10.1038/s41596-019-0234-7(link is external)

MCL1 Is Required for Maintenance of Intestinal Homeostasis and Prevention of Carcinogenesis in Mice


Healy, M. E., Boege, Y., Hodder, M. C., Bohm, F., Malehmir, M., Scherr, A. L., Jetzer, J., Chan, L. K., Parrotta, R., Jacobs, K., Clerbaux, L. A., Kreutzer, S., Campbell, A., Gilchrist, E., Gilroy, K., Rodewald, A. K., Honcharova-Biletska, H., Schimmer, R., Velez, K., Bueler, S., Cammareri, P., Kalna, G., Wenning, A. S., McCoy, K. D., Gomez de Aguero, M., Schulze-Bergkamen, H., Klose, C. S. N., Unger, K., Macpherson, A. J., Moor, A. E., Kohler, B., Sansom, O. J., Heikenwalder, M., Weber, A. (2020). Gastroenterology 159, 183-199.

DOI:10.1053/j.gastro.2020.03.017(link is external)